This clinical investigation was based upon 56 cases of primary amenorrhea and infertility for whom clomiphene citrate were administered at the Dept. of Obst. & Gynec., N.M.C., from Sept., 1965 to Dec., 1968, and the results are as follows:
1) There was observed no ovulatory cycle during 5 drug cycles in 2 cases of primary ameorrhea for whom clomiphene citrate 100 mg. were administered for 7 days.
2) There were observed 9 ovulatory cycles in -6 cases of secondary amenorrhea during total 25 drug cycles (36.0%).
3) There were observed 21 ovulatory cycles in 10 cases of total 23 cases of oligomenorrhea during total 47 drug cycles in doses of clomiphene citrate 50 mg per day for 7 days (44.6%).
4) There were observed 30 ovulatory cycles in 19 cases of total 22 cases of anovulatory cycle during total 46 drug cycles in doses of clomiphene citrate 50 mg per day for 7 days (65.2%).
5) Total pregnancies were 14;one in secondary amenorrhea,-´5 in oligomenorrhea, and 8 in anovulatory cycle patients; the secondary amenorrhea case is during preggancy. Of 5 oligomenorrhea, 2 during pregnancy, one abortion, and 2 normal term deliveries (male 1, female 1). Of 8 anovulatory cycle patients, 4 during pregnancy, one premature delivery and 3 normal term deliveries (male 2. female 1).
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